Hard transparent capsules
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As someone who has worked in the pharmaceutical industry for years, I have seen firsthand the importance of using the right type of capsules for different medications. One type of capsule that has gained popularity in recent years is the hard transparent capsule. In this article, I will explore the advantages of using hard transparent capsules, the different types available, the manufacturing process, quality control measures, applications, and a comparison with other types of capsules.
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Product Description
The table below shows the specification of gelatin used in transparent capsules:
Items | Unit | Specifications | ||||
Gel Strength 6.67%, 10℃ | g | 220-240 | ||||
Viscosity 6.67%, 60℃ | mPas | 4.8-6.5 | ||||
Visco-down 6.67% 37℃ | % | <=5 | ||||
Molsture | % | <=14 | ||||
Ashes | % | <=1 | ||||
pH 1.0%, 35℃ | 5.3-5.9 | |||||
pH Isoionlc Point | 5.2-6.0 | |||||
Insoluble Particles | % | <=0.1 | ||||
Physical Characteristics | Light yellow or yellow, translucent, slightly shiny particles or flakes; odorless and tasteless. | |||||
Transmission 450nm | % | >=80 | ||||
Transmission 620nm | % | >=93 | ||||
Sulfur dioxide (SO2) | mg/kg | <=30 | ||||
Oxidizing Substance (is H2O2) | No blue | |||||
E-Coli | 1g | Not Detected | ||||
Pseudomonas aeruginosa | 10g | Not Detected | ||||
Staphylococcus aureus | 1g | Not Detected | ||||
Salmonella | 10g | Not Detected | ||||
Total Bacteria Count | CFU/g | <=1000 | ||||
Yeast and Mould | CFU/g | <=100 | ||||
Chromium (Cr) | mg/kg | <=2 | ||||
Conductivity 1%, 30℃ | mS/cm | <=0.5 | ||||
Arsenic (As) | mg/kg | <=0.8 | ||||
Heavy Metal | mg/kg | <=50 |
What sizes of hard transparent capsules we wholesale?
most of buyers purchase #0 #1 #2 #3 #4 for human consumption.
But more sizes could be provided by us . more details are listed in below table.
More sizes in below table could be customized.
Empty transparent Capsule Size |
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Capsule Size | 000 | 00E | 00 | 0E | 0 | 1 | 2 | 3 | 4 | 5 | ||||||||||||
Empty transparent Capsule Weight (Gelatin) | ||||||||||||||||||||||
Average Weight (mg) | 158 | 143 | 123 | 107 | 99 | 76 | 61 | 48 | 38 | 28 | ||||||||||||
Tolerance | ±10 | ±10 | ±7 | ±7 | ±6 | ±5 | ±4 | ±3 | ±3 | ±2 | ||||||||||||
Empty transparent Capsule Volume Capacity (ml) | ||||||||||||||||||||||
Capacity | 1.37 | 1.00 | 0.90 | 0.78 | 0.68 | 0.48 | 0.36 | 0.27 | 0.20 | 0.13 | ||||||||||||
Empty transparent Capsule Weight Capacity by Formulation Density (mg) | ||||||||||||||||||||||
Formulation Density | ||||||||||||||||||||||
0.6 g/ml | 822 | 600 | 540 | 468 | 408 | 288 | 216 | 162 | 120 | 78 | ||||||||||||
0.8 g/ml | 1096 | 800 | 720 | 624 | 544 | 384 | 288 | 216 | 160 | 104 | ||||||||||||
1.0 g/ml | 1370 | 1000 | 900 | 780 | 680 | 480 | 360 | 270 | 200 | 130 | ||||||||||||
1.2 g/ml | 1644 | 1200 | 1080 | 936 | 816 | 576 | 432 | 324 | 240 | 156 | ||||||||||||
Empty transparent Capsule Overall Closed Length | ||||||||||||||||||||||
(mm) | 26.1 | 25.3 | 23.4 | 23.5 | 21.6 | 19.4 | 17.6 | 15.7 | 14.3 | 11.1 | ||||||||||||
Tolerance (mm) | ±0.3 | ±0.3 | ±0.3 | ±0.3 | ±0.3 | ±0.3 | ±0.3 | ±0.3 | ±0.3 | ±0.4 | ||||||||||||
inches | 1.029 | 0.996 | 0.921 | 0.909 | 0.85 | 0.764 | 0.693 | 0.618 | 0.563 | 0.437 | ||||||||||||
Tolerance inches | ±0.012 | ±0.012 | ±0.012 | ±0.012 | ±0.012 | ±0.012 | ±0.012 | ±0.012 | ±0.012 | ±0.016 | ||||||||||||
Empty transparent Capsule Individual Lengths (Cap) | ||||||||||||||||||||||
Cap (mm) | 12.95 | 12.95 | 11.80 | 11.68 | 10.85 | 9.85 | 8.80 | 8.00 | 7.20 | 6.20 | ||||||||||||
Tolerance | ±0.35 | ±0.35 | ±0.35 | ±0.35 | ±0.35 | ±0.35 | ±0.35 | ±0.35 | ±0.35 | ±0.29 | ||||||||||||
Cap (inches) | 0.510 | 0.510 | 0.464 | 0.460 | 0.427 | 0.388 | 0.346 | 0.315 | 0.283 | 0.244 | ||||||||||||
Tolerance | ±0.014 | ±0.014 | ±0.014 | ±0.014 | ±0.014 | ±0.014 | ±0.014 | ±0.014 | ±0.014 | ±0.012 | ||||||||||||
Empty transparent Capsule Individual Lengths (Body) | ||||||||||||||||||||||
Body (mm) | 22.20 | 22.20 | 20.22 | 20.19 | 18.35 | 16.40 | 15.15 | 13.45 | 12.10 | 9.30 | ||||||||||||
Tolerance | ±0.35 | ±0.35 | ±0.35 | ±0.35 | ±0.35 | ±0.35 | ±0.35 | ±0.35 | ±0.35 | ±0.29 | ||||||||||||
Body (inches) | 0.879 | 0.879 | 0.796 | 0.795 | 0.722 | 0.645 | 0.596 | 0.529 | 0.476 | 0.366 | ||||||||||||
Tolerance | ±0.014 | ±0.014 | ±0.014 | ±0.014 | ±0.014 | ±0.014 | ±0.014 | ±0.014 | ±0.014 | ±0.012 | ||||||||||||
Empty transparent Capsule External Diameter | ||||||||||||||||||||||
Cap (mm) | 9.91 | 8.58 | 8.56 | 7.65 | 7.64 | 6.96 | 6.39 | 5.85 | 5.33 | 4.91 | ||||||||||||
Cap (inches) | 0.390 | 0.338 | 0.337 | 0.301 | 0.301 | 0.274 | 0.252 | 0.230 | 0.210 | 0.193 | ||||||||||||
Body (mm) | 9.55 | 8.25 | 8.23 | 7.36 | 7.35 | 6.63 | 6.12 | 5.6 | 5.08 | 4.68 | ||||||||||||
Body (inches) | 0.375 | 0.376 | 0.322 | 0.289 | 0.289 | 0.290 | 0.240 | 0.220 | 0.200 | 0.184 | ||||||||||||
Empty transparent Capsule Quantity Per Case | ||||||||||||||||||||||
Capsules Per Box | 50,000 | 65,000 | 75,000 | 90,000 | 100,000 | 140000 | 175,000 | 200,000 | 250,000 | 350,000 |
Advantages of Using Hard Transparent Capsules
Hard transparent capsules have a range of advantages that make them a popular choice among pharmaceutical manufacturers. Firstly, the transparent nature of these capsules allows for easy visual inspection of the contents. This means that any issues with the medication inside the capsule can be identified easily, and steps can be taken to address them. Additionally, the transparency of the capsule allows for better branding opportunities, as the contents of the capsule can be seen clearly.
Another advantage of using hard transparent capsules is their ability to protect the contents from light and moisture. The capsule material is impermeable to light and moisture, which helps to maintain the stability and potency of the medication for longer periods. This is particularly important for medications that are sensitive to light and moisture, as it ensures that they remain effective for the duration of their shelf life.
Finally, hard transparent capsules are easy to swallow and have a smooth texture. This makes them an ideal choice for patients who have difficulty swallowing tablets or other types of capsules. The smooth texture of the capsule also makes it easier for the medication to be absorbed by the body.
Types of Hard Transparent Capsules
There are two main types of hard transparent capsules: gelatin and vegetarian. Gelatin capsules are made from animal by-products and are the most common type of capsule used in the pharmaceutical industry. Vegetarian capsules, on the other hand, are made from plant-based materials and are a popular choice for those who prefer a vegetarian or vegan lifestyle.
Gelatin capsules are available in different sizes and colors, making them suitable for a wide range of medications. They are also relatively easy to manufacture, which makes them a cost-effective option for pharmaceutical manufacturers. Vegetarian capsules, on the other hand, are available in fewer sizes and colors, and are slightly more expensive to manufacture. However, they are a popular choice for pharmaceutical manufacturers who wish to cater to a wider range of consumers.
Manufacturing Process of Hard Transparent Capsules
The manufacturing process of hard transparent capsules involves several steps, including the preparation of the capsule material, filling the capsules with medication, and sealing the capsules. The capsule material is prepared by mixing gelatin or vegetarian materials with water and other ingredients. This mixture is then heated and cooled to form a gel-like substance that is used to make the capsules.
The medication is then filled into the capsules using a filling machine. The capsules are then sealed using a sealing machine to ensure that the medication remains secure within the capsule. The finished capsules are then inspected for quality control purposes before being packaged and shipped to pharmacies and other medical facilities.
Quality Control Measures for Hard Transparent Capsules
Quality control measures are an essential part of the manufacturing process for hard transparent capsules. The capsules must meet certain standards to ensure that they are safe and effective for use. Quality control measures include inspecting the capsules for defects, testing the capsules for strength and stability, and ensuring that the medication inside the capsule is of the correct dosage.
Pharmaceutical manufacturers also conduct stability studies to determine the shelf life of the medication inside the capsule. This involves storing the capsules under different conditions, such as temperature and humidity, to determine how well the medication holds up over time.
Applications of Hard Transparent Capsules
Hard transparent capsules are used for a wide range of medications, including vitamins, supplements, and prescription medications. They are particularly popular for medications that are sensitive to light and moisture, as the capsule material provides a protective barrier against these elements.
Hard transparent capsules are also a popular choice for medications that require a precise dosage. The capsules can be filled with a specific amount of medication, which ensures that patients receive the correct dosage every time.
Comparison Between Hard Transparent Capsules and Other Types of Capsules
Hard transparent capsules have several advantages over other types of capsules. For example, they are easier to swallow than tablets, and their transparent nature allows for easy visual inspection of the contents. They also provide a protective barrier against light and moisture, which helps to maintain the stability and potency of the medication.
Other types of capsules, such as soft gelatin capsules and enteric-coated capsules, have their own advantages. Soft gelatin capsules are suitable for liquid medications and have a longer shelf life than other types of capsules. Enteric-coated capsules are designed to protect the medication from stomach acid, which makes them an ideal choice for medications that need to be absorbed in the small intestine.
Conclusion
Hard transparent capsules have become a popular choice for pharmaceutical manufacturers due to their advantages over other types of capsules. They provide a protective barrier against light and moisture, are easy to swallow, and allow for easy visual inspection of the contents. With their range of applications and ability to protect the contents, they are an ideal choice for a wide range of medications.